Genetic Transformation and Tool Development

Overview:  The ability to genetically modify microorganisms is foundational to performing rational strain engineering, but most organisms are not transformable when first isolated. We are able to develop initial transformation methodologies and protocols for new organisms or improve upon existing ones. We can further develop high throughput tools for more rapid strain modification in these […]

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Fungal Genomics, Synthetic Biology and Bioprocess Development

Overview:  The ABF houses the filamentous fungal and non-model yeast synthetic biology capability unique within the government laboratories. This effort also comprises integrated fungal genetic tool and medium scale (15-120L) bioprocess development capability. Samples for Testing and Learning by a systems biology approach are generated from large shake flask experimental capabilities or through one of […]

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