Lipidomics
Comprehensive analysis of lipids in biological systems
Lipidomics is the characterization of the complete set of lipids (lipidome) in a biological system for qualitative and quantitative purposes.
Lipidomics, one of the multiomics technologies, can be used for the following applications in synthetic biology research:
- Providing detailed insights into the lipid composition of engineered cells or bioreactor systems
- Optimizing cellular membrane properties
- Understanding metabolic pathways of target lipid or lipid-like molecules
- Identifying potential targets for further manipulation to enhance desired cellular functions in synthetic constructs
USE CASE
Agile BioFoundry researchers used lipidomics data in a multi-omics study of Rhodosporidium toruloides to develop a genome-scale metabolic network model that includes the biosynthetic pathways for diverse classes of lipids.
Fatty acid composition of R. toruloides in different media conditions and segmented linear regression.