Capabilities
Uniting world-class national laboratory facilities through a Design-Build-Test-Learn platform
Design
Develop bioprocesses for your desired target molecules, as well as the necessary tools to build out pathways in a host organism.
Visually design combinatorial libraries of DNA for downstream construction. Learn more about DIVA bioCAD.
Perform structure based design of enzymes for gain-of-function. Learn more about Computational Protein Design.
Guide synthetic biology in a systematic fashion through machine learning and probabilistic modeling techniques. Learn more about Pathway Design through Machine Learning.
Rapidly develop bioproducts through metabolic engineering and bioprocessing strategies. Learn more about Pathway Development and Evaluation.
Build
Transform Design concepts and specifications into physical engineered microbial host organisms, ready to be Tested.
Physically fabricate and sequence validate DNA constructs of interest. Learn more about DIVA DNA Sequence Construction and Validation.
Leverage tools, methodologies and protocols for using new organisms to enable efficient biomanufacturing. Learn more about Genetic Tools.
Obtain production strains with beneficial mutations. Learn more about Adaptive Laboratory Evolution.
Automation for high-throughput, fast and affordable results. Learn more about Automated Lab.
Test
Understand how an engineered pathway behaves in your host organism and measure performance.
Tune gene expression to improve growth and productivity of engineered strains. Learn more about Riboregulators.
Quantitatively survey libraries of engineered strains. Learn more about High Throughput Screening.
Measure metabolites both non-invasively and in real time. Learn more about Biosensors.
A repository for Learn-friendly formatting of multiomics measurements. Learn more about Experiment Data Depot.
Quantify metabolite levels in engineered microbes to identify bottlenecks. Learn more about Metabolomics.
Understand gene expression in biological systems. Learn more about Transcriptomics.
Comprehensive analysis of lipids in biological systems. Learn more about Lipidomics.
Automation for high-throughput, fast and affordable results. Learn more about Automated Lab.
Learn
Use various methods to translate your experimental data into predictions for the design of future pathways and processes.
Gain key insights into metabolic processes. Learn more about Mechanistic Models.
Guide metabolic engineering efforts, make predictions, and optimize production. Learn more about Artificial Intelligence.
Interpret multi-omics measurements. Learn more about AgileBioCyc.
Technoeconomic Analysis and Life Cycle Assessment
Identify bottlenecks in bioprocessing for improved economic feasibility and environmental impact, and prioritize R&D.
Host Onboarding
Unlock the potential of non-model microbes.
Scale Up
Translate technologies to industry scale.