Pathway Development and Evaluation

Enabling rapid development of bioproducts

Pathway Development and Evaluation encompasses the design of metabolic engineering and bioprocessing strategies to enable production of exemplary targets associated with various beachhead molecules, metabolic intermediates that can be converted into several bioproducts, as shown on the map linked below. Potential beachheads are highlighted in gray, beachheads we are currently working on are in green, and Agile BioFoundry target molecules are in blue.

Agile BioFoundry's metabolic map, which represents metabolic pathways that have been described for conversion of biomass derived carbohydrates to industrial chemicals.
This map represents a compilation of metabolic pathways that have been described for conversion of biomass-derived carbohydrates to industrial chemicals. Adapted by permission from Springer Nature Customer Service Centre GmbH: Nature, Nature Catalysis, A comprehensive metabolic map for production of bio-based chemicals, Lee, S.Y., et al., © 2019. View a full-size PDF here.

Pathway Development and Evaluation using exemplary targets will enable rapid development of strategies for production of related bioproducts; rather than starting from scratch, potential partners interested in developing strategies for production of their product of interest can leverage metabolic engineering and process scale-up strategies as well as techno-economic and life cycle assessment developed for an exemplary product associated with the same beachhead.

Learn more about how this capability can be leveraged towards your own products of interest in this video.

In this way, the Agile BioFoundry’s pathway development and evaluation is precompetitive research & development that serves as an infrastructure investment to reduce the time to bioprocess scale-up for a wide range of potential products. 


  • Argonne National Laboratory
  • Los Alamos National Laboratory
  • Lawrence Berkeley National Laboratory
  • National Renewable Energy Laboratory
  • Oak Ridge National Laboratory
  • Pacific Northwest National Laboratory
  • Sandia National Laboratories